Effectiveness of Nursing-Led Pain Management Interventions for Adults with Breast Cancer: A Systematic Review
DOI:
https://doi.org/10.67903/ijroms0425Keywords:
Breast Cancer, Cancer Pain, Nursing-Led Interventions, Pain Management, Palliative CareAbstract
This systematic review examined nursing-led interventions for managing pain in adults with breast cancer. Following PRISMA, 1,196 records were identified from databases; 1,136 were removed before screening (502 duplicates and 634 marked ineligible by automation tools), 60 records were screened, 55 reports were sought, 41 could not be retrieved, and 14 studies were included. Included studies were classified by population: none of the 14 was restricted to Stage IV breast cancer (Category 1); five involved advanced or metastatic cancer or breast cancer populations (Category 2); and nine came from broader cancer populations or were contextual (Category 3). Findings were synthesized narratively, and study-level sample sizes, comparators, and effect estimates are tabulated; appraisal ratings of the rated studies ranged from moderate to high. Pain education showed a small pooled reduction in pain compared with standard care in broader cancer samples (12 studies; pooled effect −0.36), and one trial in metastatic cancer reported lower pain severity after pain self-management education. In contrast, a meta-analysis of 41 nurse-led symptom-management trials found no clear pain benefit, and a PRO-SELF trial (n = 64) improved self-efficacy, quality of life, and mood without significant pain differences. Two included reports were descriptive conference abstracts and one was a trial protocol, so they provided no comparative pain data. The evidence therefore supports nursing-led education and self-management as promising but indirect strategies for Stage IV breast cancer pain; Stage IV-specific comparative trials are needed. Implementation depends on nurse training, institutional support, medication access, and culturally responsive care.
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Alsaiari, S., Alhofaian, A., & Tunsi, A. (2024). Nurses' knowledge, perceived barriers and practices regarding cancer pain management: A scoping review. Indian Journal of Palliative Care, 30(1), 1–9. https://doi.org/10.25259/IJPC_232_2023
Dave, R. V., Bromley, H., Taxiarchi, V. P., Camacho, E., Chatterjee, S., Barnes, N., et al. (2022). No association between breast pain and breast cancer: A prospective cohort study of 10,830 symptomatic women presenting to a breast cancer diagnostic clinic. British Journal of General Practice, 72(717), e234– e243. https://doi.org/10.3399/BJGP.2021.0475
Department of Health. (2022). Breast cancer national clinical practice guidelines. National Integrated Cancer Control Program, Disease Prevention and Control Bureau. https://psmo.org.ph/wp-content/uploads/2023/06/CPG-Breast-Cancer-National-Clinical-Practice-Guidelines.pdf
Devine, E. C. (2003). Meta-analysis of the effect of psychoeducational interventions on pain in adults with cancer. Oncology Nursing Forum, 30(1), 75–89.
González-Martín, A. M., Aguilera-García, I., Castellote-Caballero, Y., Rivas-Campo, Y., Bernal-Suárez, A., & Aibar-Almazán, A. (2023). Effectiveness of therapeutic education in patients with cancer pain: Systematic review and meta-analysis. Cancers, 15(16), Article 4123. https://doi.org/10.3390/cancers15164123
Guven, D. C., Aktepe, O. H., Berk, Z., Guner, G., Taban, H., Aktas, B. Y., Duran, Z. C., Akin, S., Arik, Z., Kertmen, N., Kilickap, S., Turker, A., & Dizdar, O. (2019). Embedded outpatient palliative care service within the oncology clinic: Preliminary experience in Hacettepe Oncology Hospital [Conference abstract]. Annals of Oncology, 30(Suppl. 5), v666. https://doi.org/10.1093/annonc/mdz261.017
Hammer, M. J., Ercolano, E. A., Wright, F., Dickson, V. V., Chyun, D., & Melkus, G. D. (2015). Self- management for adult patients with cancer: An integrative review. Cancer Nursing, 38(2), E10–E26. https://doi.org/10.1097/NCC.0000000000000122
Javier, F. O., Irawan, C., Mansor, M. B., Sriraj, W., Tan, K. H., & Thinh, D. H. Q. (2016). Cancer pain management insights and reality in Southeast Asia: Expert perspectives from six countries. Journal of Global Oncology, 2(4), 235–243. https://doi.org/10.1200/JGO.2015.001859
Kelly, D., Campbell, P., Torrens, C., Charalambous, A., Östlund, U., Eicher, M., Larsson, M., Nohavova, I., Olsson, C., Simpson, M., Patiraki, E., Sharp, L., Wiseman, T., Oldenmenger, W., & Wells, M. (2022). The effectiveness of nurse-led interventions for cancer symptom management 2000–2018: A systematic review and meta-analysis. Health Sciences Review, 4, Article 100052. https://doi.org/10.1016/j.hsr.2022.100052
Li, P., Guo, Y. J., Tang, Q., & Yang, L. (2018). Effectiveness of nursing intervention for increasing hope in patients with cancer: A meta-analysis. Revista Latino-Americana de Enfermagem, 26, Article e2937. https://doi.org/10.1590/1518-8345.1920.2937
Musavi, M., Jahani, S., Asadizaker, M., Maraghi, E., & Razmjoo, S. (2021). The effect of pain self-management education on pain severity and quality of life in metastatic cancer patients. Asia-Pacific Journal of Oncology Nursing, 8(4), 419–426. https://doi.org/10.4103/apjon.apjon-2097
Park, Y. J., & Lee, M. K. (2022). Effects of nurse-led nonpharmacological pain interventions for patients with cancer: A systematic review and meta-analysis. Journal of Nursing Scholarship, 54(4), 422–433. https://doi.org/10.1111/jnu.12750
Plinsinga, M. L., Singh, B., Rose, G. L., Clifford, B., Bailey, T. G., Spence, R. R., Turner, J., Coppieters, M. W., McCarthy, A. L., & Hayes, S. C. (2023). The effect of exercise on pain in people with cancer: A systematic review with meta-analysis. Sports Medicine, 53(9), 1737–1752. https://doi.org/10.1007/s40279-023-01862-9
Ran, R., Ying, Y., & Zhang, W. (2023). Effects of music intervention on anxiety, depression symptoms and quality of life in breast cancer patients: A meta-analysis. Actas Españolas de Psiquiatría, 51(6), 250– 261. https://pmc.ncbi.nlm.nih.gov/articles/PMC10847666/
Triglianos, T., Sorah, J. D., Cao, F., Bunch, J., Collichio, F. A., Allard, M., et al. (2023). Rapid care transition: Implementation of an undiagnosed cancer clinic [Conference abstract]. JCO Oncology Practice, 19(11 Suppl.), 80. https://doi.org/10.1200/OP.2023.19.11_suppl.80
Wang, C. C., Geraghty, S., Fox-Harding, C., & Wang, C. (2022). Effects of a nurse-led Tai Chi programme on improving quality of life, mental wellbeing, and physical function of women with breast cancer: Protocol for a randomized controlled trial. Women's Health, 18, Article 17455057221127813. https://doi.org/10.1177/17455057221127813
World Health Organization. (2019). WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents. https://www.who.int/publications/i/item/9789241550390
Yin, X., Chu, Z. J., Ni, Y. Y., Li, H. W., & Li, H. Y. (2023). The influence of PRO-SELF cancer pain control programme on patients' self-management ability. International Journal of Integrated Care, 23(4), Article 8. https://doi.org/10.5334/ijic.7543
Zhou, L., Liu, X.-L., Tan, J.-Y., Yu, H.-P., Pratt, J., & Peng, Y.-Q. (2015). Nurse-led educational interventions on cancer pain outcomes for oncology outpatients: A systematic review. International Nursing Review, 62(2), 218–230. https://doi.org/10.1111/inr.12172
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